Tuff Yen

A Career in Venture Capital
Est. 2004 · Seraph Group

Teaching successful individuals how professional investors create wealth through ownership of private enterprises.

CEO of Seraph Group & Seraph Direct | $200M+ Invested Across 180+ Startups
Explore the Groups About Tuff
I / The Network

His firm, and a new local initiative

Over two decades, Tuff built Seraph Group into a global investment firm. Now he is personally forming private angel groups, city by city — small circles who learn how early-stage investing works, see real deal flow, and invest together.

The Firm

The firm he built: Seraph Group

Tuff is the founder, CEO, and General Partner of Seraph Group — the global investment firm behind two decades of his work, and the engine of deal flow, diligence, and discipline he draws on. More recently, he launched two further efforts under the firm — Seraph Direct and the Seraph Research Foundation — described below.

Seraph Group Visit seraphgroup.net ↗
The Angel Groups · by city
Tuff Yen, Founder of Seraph Group

Tuff Yen is a career venture capitalist who has personally led over $200 million of investment into more than 180 early-stage technology companies.

He began as a bioengineer at Genentech and Amgen, two of the world's leading biotechnology companies. After earning his MBA from the Yale School of Management, he entered venture capital at Chemical Venture Partners — the private equity arm of Chemical Bank (now JPMorgan) — before joining Hambrecht & Quist's affiliated fund in San Francisco.

In 2004 he founded Seraph Group and invented the Structured Angel Fund™ (SAF™). His network spans more than 400 individuals across 120 cities in North America, Europe, and Asia.

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Early career
Genentech · Amgen
Bioengineer
Yale
School of Management
MBA
Wall St.
JPMorgan
Chemical Venture Partners
San Francisco
Hambrecht & Quist
Affiliated venture fund
2004
Seraph Group
Founded · invented the SAF™
2025
Seraph Direct
Launched the co-investment platform
The Structured Angel Fund
An institutional discipline, built for individuals.

In 2004, Tuff invented the Structured Angel Fund™ (SAF™) — a proprietary venture fund structure that gives angel investors and family offices the access, discipline, and diversification of an institutional venture capital firm, without the institution.

It is the same philosophy behind the angel groups forming across Georgia today: learn how the professionals do it, then put that knowledge to work — together.

i.

Access

Into the same private rounds institutional funds compete for.

ii.

Discipline

Professional sourcing, diligence, and deal structure on every position.

iii.

Diversification

A portfolio wide enough to catch the rare, outsized winner.

What he backs
Stage
Early-stage technology
Geography
North America, Europe & Asia
Structure
SAF™ & Seraph Direct
AerospaceCybersecurityMedical DevicesEnterprise SoftwareFintechDeep Tech
Most Recent Exit Noctrix Health acquired by ResMed for $340M A Seraph Group portfolio company · 2026
$200M+
Capital Deployed
180+
Companies Backed
400+
Investor Network
120+
Cities Reached
The Power Law

A few investments return the entire fund

Most startups return little — and a rare few return everything. That is why disciplined investors build a diversified portfolio: enough quality shots to catch the outlier.

A representative venture portfolio — returns, not counts.
Get Involved

Two ways to take part

Speaker, ACA Summit 2026 Angel Capital Association member Founder, Seraph Research Foundation
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